Heightened expression of MICA enhances the cytotoxicity of NK cells or CD8(+)T cells to human corneal epithelium in vitro

BACKGROUND: Major-histocompatibility-complex class I-related chain A (MICA) antigens are the ligands of NKG2D, which is an activating or coactivating receptor expressed on human NK cells and CD8(+)T cells. We sought to determine whether MICA expression in human corneal epithelium (HCE) could affect...

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Detalhes bibliográficos
Main Authors: Hong, Jiaxu, Qiu, Ting, Qian, Tingting, Li, Gang, Yu, Xiaobo, Chen, Junyi, Le, Qihua, Sun, Xinghuai, Xu, Jianjiang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3733519/
https://ncbi.nlm.nih.gov/pubmed/22475346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2415-12-6
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