Epigenetic stability of repressed states involving the histone variant macroH2A revealed by nuclear transfer to Xenopus oocytes

How various epigenetic mechanisms restrict chromatin plasticity to determine the stability of repressed genes is poorly understood. Nuclear transfer to Xenopus oocytes induces the transcriptional reactivation of previously silenced genes. Recent work suggests that it can be used to analyze the epige...

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Hlavní autoři: Pasque, Vincent, Halley-Stott, Richard P., Gillich, Astrid, Garrett, Nigel, Gurdon, John B.
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324342/
https://ncbi.nlm.nih.gov/pubmed/22064467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.2.6.17799
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