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Imexon Induces an Oxidative Endoplasmic Reticulum Stress Response in Pancreatic Cancer Cells
Oxidative protein folding in the endoplasmic reticulum (ER) requires strict regulation of redox homeostasis. Disruption of the lumenal redox balance induces an integrated ER stress response that is associated with reduced protein translation, increased chaperone activity, and ultimately cell death....
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3324333/ https://ncbi.nlm.nih.gov/pubmed/22275514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-11-0359 |
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