The Antitumor Agent Imexon Activates Antioxidant Gene Expression: Evidence for an Oxidative Stress Response

PURPOSE: The aim of this study was to identify biomarkers that may be predictive for the clinical activity of the redox-active antitumor agent imexon. EXPERIMENTAL DESIGN: cDNA microarray and quantitative real-time PCR were used to identify global changes in gene expression in peripheral blood monon...

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Detalhes bibliográficos
Main Authors: Baker, Amanda F., Landowski, Terry, Dorr, Robert, Tate, Wendy R., Gard, Jaime M.C., Tavenner, Breonna E., Dragovich, Tomislov, Coon, Amy, Powis, Garth
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989931/
https://ncbi.nlm.nih.gov/pubmed/17545547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-06-0873
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