Lataa...

Soluble oligomerization provides a beneficial fitness effect on destabilizing mutations

Mutations create the genetic diversity on which selective pressures can act, yet also create structural instability in proteins. How, then, is it possible for organisms to ameliorate mutation-induced perturbations of protein stability while maintaining biological fitness and gaining a selective adva...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Bershtein, Shimon, Wu, Wanmeng, Shakhnovich, Eugene I.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323985/
https://ncbi.nlm.nih.gov/pubmed/22411825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1118157109
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!