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Noncanonical repression of translation initiation through small RNA recruitment of the RNA chaperone Hfq

The RNA chaperone Hfq is mostly known to help small regulatory RNAs (sRNAs) interact with target mRNAs to block initiating ribosomes. In this model, whereas the sRNA is directly competing with initiating 30S ribosomal subunits, Hfq plays only an indirect role, allowing optimal sRNA–mRNA pairing. Her...

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Hlavní autoři: Desnoyers, Guillaume, Massé, Eric
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323883/
https://ncbi.nlm.nih.gov/pubmed/22474262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.182493.111
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