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Antagonistic functions between the RNA chaperone Hfq and an sRNA regulate sensitivity to the antibiotic colicin

The RNA chaperone Hfq is a key regulator of the function of small RNAs (sRNAs). Hfq has been shown to facilitate sRNAs binding to target mRNAs and to directly regulate translation through the action of sRNAs. Here, we present evidence that Hfq acts as the repressor of cirA mRNA translation in the ab...

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Detalhes bibliográficos
Main Authors: Salvail, Hubert, Caron, Marie-Pier, Bélanger, Justine, Massé, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3801439/
https://ncbi.nlm.nih.gov/pubmed/24065131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.205
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