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Small RNA-induced mRNA degradation achieved through both translation block and activated cleavage
Small RNA (sRNA)-induced mRNA degradation occurs through binding of an sRNA to a target mRNA with the concomitant action of the RNA degradosome, which induces an endoribonuclease E (RNase E)-dependent cleavage and degradation of the targeted mRNA. Because many sRNAs bind at the ribosome-binding site...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Cold Spring Harbor Laboratory Press
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3042161/ https://ncbi.nlm.nih.gov/pubmed/21289064 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.2001711 |
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