Small RNA-induced mRNA degradation achieved through both translation block and activated cleavage

Small RNA (sRNA)-induced mRNA degradation occurs through binding of an sRNA to a target mRNA with the concomitant action of the RNA degradosome, which induces an endoribonuclease E (RNase E)-dependent cleavage and degradation of the targeted mRNA. Because many sRNAs bind at the ribosome-binding site...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Prévost, Karine, Desnoyers, Guillaume, Jacques, Jean-François, Lavoie, François, Massé, Eric
פורמט: Artigo
שפה:Inglês
יצא לאור: Cold Spring Harbor Laboratory Press 2011
נושאים:
Research Paper
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042161/
https://ncbi.nlm.nih.gov/pubmed/21289064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.2001711
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