Divergent Roles of p75(NTR) and Trk Receptors in BDNF's Effects on Dendritic Spine Density and Morphology

Activation of TrkB receptors by brain-derived neurotrophic factor (BDNF) followed by MAPK/ERK signaling increases dendritic spine density and the proportion of mature spines in hippocampal CA1 pyramidal neurons. Considering the opposing actions of p75(NTR) and Trk receptors in several BDNF actions o...

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Bibliographische Detailangaben
Hauptverfasser: Chapleau, Christopher A., Pozzo-Miller, Lucas
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323862/
https://ncbi.nlm.nih.gov/pubmed/22548193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/578057
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