Divergent Roles of p75(NTR) and Trk Receptors in BDNF's Effects on Dendritic Spine Density and Morphology

Activation of TrkB receptors by brain-derived neurotrophic factor (BDNF) followed by MAPK/ERK signaling increases dendritic spine density and the proportion of mature spines in hippocampal CA1 pyramidal neurons. Considering the opposing actions of p75(NTR) and Trk receptors in several BDNF actions o...

Full description

Saved in:
Bibliographic Details
Main Authors: Chapleau, Christopher A., Pozzo-Miller, Lucas
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323862/
https://ncbi.nlm.nih.gov/pubmed/22548193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/578057
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items