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Stable Mutated tau441 Transfected SH-SY5Y Cells as Screening Tool for Alzheimer’s Disease Drug Candidates

The role of hyperphosphorylation of the microtubule-associated protein tau in the pathological processes of several neurodegenerative diseases is becoming better understood. Consequently, development of new compounds capable of preventing tau hyperphosphorylation is an increasingly hot topic. For th...

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Autors principals: Löffler, Tina, Flunkert, Stefanie, Taub, Nicole, Schofield, Emma L., Ward, Malcolm A., Windisch, Manfred, Hutter-Paier, Birgit
Format: Artigo
Idioma:Inglês
Publicat: Humana Press Inc 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323815/
https://ncbi.nlm.nih.gov/pubmed/22351109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12031-012-9716-6
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