טוען...
The specific role of pRb in p16(INK4A)-mediated arrest of normal and malignant human breast cells
RB family proteins pRb, p107 and p130 have similar structures and overlapping functions, enabling cell cycle arrest and cellular senescence. pRb, but not p107 or p130, is frequently mutated in human malignancies. In human fibroblasts acutely exposed to oncogenic ras, pRb has a specific role in suppr...
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| Main Authors: | , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Landes Bioscience
2012
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3323799/ https://ncbi.nlm.nih.gov/pubmed/22333593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.11.5.19492 |
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