JNK2 and JNK3 are major regulators of axonal injury-induced retinal ganglion cell death

Glaucoma is a neurodegenerative disease characterized by the apoptotic death of retinal ganglion cells (RGCs). The primary insult to RGCs in glaucoma is thought to occur to their axons as they exit the eye in the optic nerve head. However, pathological signaling pathways that exert central roles in...

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Main Authors: Fernandes, Kimberly A., Harder, Jeffrey M., Fornarola, Laura B, Freeman, Robert S, Clark, Abbot F., Pang, Iok-Hou, John, Simon W.M., Libby, Richard T.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323666/
https://ncbi.nlm.nih.gov/pubmed/22353563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2012.02.003
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