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Activation of Cell Cycle Arrest and Apoptosis by the Proto-Oncogene Pim-2
Potent survival effects have been ascribed to the serine/threonine kinase proto-oncogene PIM-2. Elevated levels of PIM-2 are associated with various malignancies. In human cells, a single Pim-2 transcript gives rise mainly to two protein isoforms (34, 41 kDa) that share an identical catalytic site b...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3323563/ https://ncbi.nlm.nih.gov/pubmed/22506047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034736 |
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