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The PIM-2 Kinase Is an Essential Component of the Ultraviolet Damage Response That Acts Upstream to E2F-1 and ATM

The oncogenic nature ascribed to the PIM-2 kinase relies mostly on phosphorylation of substrates that act as pro-survival/anti-apoptotic factors. Nevertheless, pro-survival effects can also result from activating DNA repair mechanisms following damage. In this study, we addressed the possibility tha...

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Detalhes bibliográficos
Main Authors: Zirkin, Shahar, Davidovich, Ateret, Don, Jeremy
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724634/
https://ncbi.nlm.nih.gov/pubmed/23760264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.458851
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