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Tissue-type plasminogen activator has a neuroprotective effect in the ischemic brain mediated by neuronal TNF-α
Cerebral cortical neurons have a heightened sensitivity to hypoxia and their survival depends on their ability to accommodate to changes in the concentration of oxygen in their environment. Tissue-type plasminogen activator (tPA) is a serine proteinase that activates the zymogen plasminogen into pla...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3323291/ https://ncbi.nlm.nih.gov/pubmed/21792242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2011.106 |
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