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Activation of Sterol-response Element-binding Proteins (SREBP) in Alveolar Type II Cells Enhances Lipogenesis Causing Pulmonary Lipotoxicity

Pulmonary inflammation is associated with altered lipid synthesis and clearance related to diabetes, obesity, and various inherited metabolic disorders. In many tissues, lipogenesis is regulated at the transcriptional level by the activity of sterol-response element-binding proteins (SREBP). The rol...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Plantier, Laurent, Besnard, Valérie, Xu, Yan, Ikegami, Machiko, Wert, Susan E., Hunt, Alan N., Postle, Anthony D., Whitsett, Jeffrey A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323060/
https://ncbi.nlm.nih.gov/pubmed/22267724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.303669
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