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Conditional deletion of Abca3 in alveolar type II cells alters surfactant homeostasis in newborn and adult mice
ATP-binding cassette A3 (ABCA3) is a lipid transport protein required for synthesis and storage of pulmonary surfactant in type II cells in the alveoli. Abca3 was conditionally deleted in respiratory epithelial cells (Abca3(Δ/Δ)) in vivo. The majority of mice in which Abca3 was deleted in alveolar t...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Physiological Society
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2867401/ https://ncbi.nlm.nih.gov/pubmed/20190032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00409.2009 |
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