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Conditional deletion of Abca3 in alveolar type II cells alters surfactant homeostasis in newborn and adult mice

ATP-binding cassette A3 (ABCA3) is a lipid transport protein required for synthesis and storage of pulmonary surfactant in type II cells in the alveoli. Abca3 was conditionally deleted in respiratory epithelial cells (Abca3(Δ/Δ)) in vivo. The majority of mice in which Abca3 was deleted in alveolar t...

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Bibliografski detalji
Glavni autori: Besnard, Valérie, Matsuzaki, Yohei, Clark, Jean, Xu, Yan, Wert, Susan E., Ikegami, Machiko, Stahlman, Mildred T., Weaver, Timothy E., Hunt, Alan N., Postle, Anthony D., Whitsett, Jeffrey A.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867401/
https://ncbi.nlm.nih.gov/pubmed/20190032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00409.2009
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