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Examination of Mechanism of N-Acetyl-1-d-myo-inosityl-2-amino-2-deoxy-α-d-glucopyranoside Deacetylase (MshB) Reveals Unexpected Role for Dynamic Tyrosine

Actinomycetes are a group of Gram-positive bacteria that includes pathogenic mycobacterial species, such as Mycobacterium tuberculosis. These organisms do not have glutathione and instead utilize the small molecule mycothiol (MSH) as their primary reducing agent and for the detoxification of xenobio...

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Библиографические подробности
Главные авторы: Huang, Xinyi, Hernick, Marcy
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323023/
https://ncbi.nlm.nih.gov/pubmed/22315231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.320184
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