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Interaction between the Msh2 and Msh6 Nucleotide-binding Sites in the Saccharomyces cerevisiae Msh2-Msh6 Complex

Indirect evidence has suggested that the Msh2-Msh6 mispair-binding complex undergoes conformational changes upon binding of ATP and mispairs, resulting in the formation of Msh2-Msh6 sliding clamps and licensing the formation of Msh2-Msh6-Mlh1-Pms1 ternary complexes. Here, we have studied eight mutan...

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Detalhes bibliográficos
Main Authors: Hargreaves, Victoria V., Shell, Scarlet S., Mazur, Dan J., Hess, Martin T., Kolodner, Richard D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838348/
https://ncbi.nlm.nih.gov/pubmed/20089866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.096388
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