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Biochemical basis for dominant mutations in the Saccharomyces cerevisiae MSH6 gene
Here, the ATP-binding, ATP hydrolysis, mispair-binding, sliding clamp formation, and Mlh1–Pms1 complex interaction properties of dominant mutant Msh2–Msh6 complexes have been characterized. The results demonstrate two mechanisms for dominance. In one, seen with the Msh6-S1036P and Msh6-G1067D mutant...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2006
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1334674/ https://ncbi.nlm.nih.gov/pubmed/16407100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510078103 |
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