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N-Alkyl derivatives of diosgenyl 2-amino-2-deoxy-β-D-glucopyranoside; synthesis and antimicrobial activity

Diosgenyl 2-amino-2-deoxy-β-D-glucopyranoside is a synthetic saponin exhibiting attractive pharmacological properties. Different pathways tested by us to obtain this glycoside are summarized here. Moreover, the synthesis of N-alkyl and N,N-dialkyl derivatives of the glucopyranoside is presented. Eva...

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Detalhes bibliográficos
Publicado no:Beilstein J Org Chem
Main Authors: Walczewska, Agata, Grzywacz, Daria, Bednarczyk, Dorota, Dawgul, Małgorzata, Nowacki, Andrzej, Kamysz, Wojciech, Liberek, Beata, Myszka, Henryk
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4464337/
https://ncbi.nlm.nih.gov/pubmed/26124888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.11.97
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