Contribution of Host Nucleoporin 62 in HIV-1 Integrase Chromatin Association and Viral DNA Integration

HIV-1 integration is promoted by viral integrase (IN) and its cellular cofactors. The lens epithelium-derived growth factor (LEDGF/p75), an IN interacting cellular cofactor, has been shown to play an important role in HIV-1 chromatin targeting and integration. However, whether other cellular cofacto...

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Bibliografiska uppgifter
Huvudupphovsmän: Ao, Zhujun, Jayappa, Kallesh Danappa, Wang, Binchen, Zheng, Yingfeng, Wang, Xiaoxia, Peng, Jinyu, Yao, Xiaojian
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2012
Ämnen:
Microbiology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322980/
https://ncbi.nlm.nih.gov/pubmed/22308026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.317057
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