Membrane Type 1 Matrix Metalloproteinase (MT1-MMP) Ubiquitination at Lys(581) Increases Cellular Invasion through Type I Collagen

Membrane type 1 matrix metalloproteinase (MT1-MMP/MMP14) is a zinc-dependent type I transmembrane metalloproteinase playing pivotal roles in the regulation of pericellular proteolysis and cellular migration. Elevated expression levels of MT1-MMP have been demonstrated to correlate with a poor progno...

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Detalhes bibliográficos
Main Authors: Eisenach, Patricia A., de Sampaio, Pedro Corrêa, Murphy, Gillian, Roghi, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322893/
https://ncbi.nlm.nih.gov/pubmed/22315223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.306340
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