Chargement en cours...

Single-molecule sequence detection via microfluidic planar extensional flow at a stagnation point

We demonstrate the use of a microfluidic stagnation point flow to trap and extend single molecules of double-stranded (ds) genomic DNA for detection of target sequences along the DNA backbone. Mutant EcoRI-based fluorescent markers are bound sequence-specifically to fluorescently labeled ds λ-DNA. T...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Dylla-Spears, Rebecca, Townsend, Jacqueline E., Jen-Jacobson, Linda, Sohn, Lydia L., Muller, Susan J.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322643/
https://ncbi.nlm.nih.gov/pubmed/20358051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b926847b
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!