Application of DEN refinement and automated model building to a difficult case of molecular-replacement phasing: the structure of a putative succinyl-diaminopimelate desuccinylase from Corynebacterium glutamicum

Phasing by molecular replacement remains difficult for targets that are far from the search model or in situations where the crystal diffracts only weakly or to low resolution. Here, the process of determining and refining the structure of Cgl1109, a putative succinyl-diaminopimelate desuccinylase f...

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Hauptverfasser: Brunger, Axel T., Das, Debanu, Deacon, Ashley M., Grant, Joanna, Terwilliger, Thomas C., Read, Randy J., Adams, Paul D., Levitt, Michael, Schröder, Gunnar F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Union of Crystallography 2012
Schlagworte:
Research Papers
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322598/
https://ncbi.nlm.nih.gov/pubmed/22505259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S090744491104978X
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