Antibody Colocalization Microarray: A Scalable Technology for Multiplex Protein Analysis in Complex Samples

DNA microarrays were rapidly scaled up from 256 to 6.5 million targets, and although antibody microarrays were proposed earlier, sensitive multiplex sandwich assays have only been scaled up to a few tens of targets. Cross-reactivity, arising because detection antibodies are mixed, is a known weaknes...

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Hlavní autoři: Pla-Roca, M., Leulmi, R. F., Tourekhanova, S., Bergeron, S., Laforte, V., Moreau, E., Gosline, S. J. C., Bertos, N., Hallett, M., Park, M., Juncker, D.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Biochemistry and Molecular Biology 2012
Témata:
Technological Innovation and Resources
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322566/
https://ncbi.nlm.nih.gov/pubmed/22171321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M111.011460
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