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Simple, scalable, and ultrasensitive tip-based identification of protease substrates

Proteases are in the center of many diseases, and consequently, proteases and their substrates are important drug targets as represented by an estimated 5–10% of all drugs under development. Mass spectrometry has been an indispensable tool for the discovery of novel protease substrates, particularly...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Shema, Gerta, Nguyen, Minh T. N., Solari, Fiorella A., Loroch, Stefan, Venne, A. Saskia, Kollipara, Laxmikanth, Sickmann, Albert, Verhelst, Steven H. L., Zahedi, René P.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880100/
https://ncbi.nlm.nih.gov/pubmed/29358340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.TIR117.000302
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