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JAZ mediates G(1) cell cycle arrest by interacting with and inhibiting E2F1
We discovered and reported JAZ as a unique dsRNA binding zinc finger protein that functions as a direct, positive regulator of p53 transcriptional activity to mediate G(1) cell cycle arrest in a mechanism involving upregulation of the p53 target gene, p21. We now find that JAZ can also negatively re...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Landes Bioscience
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3322471/ https://ncbi.nlm.nih.gov/pubmed/21715977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.14.16587 |
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