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JAZ mediates G(1) cell-cycle arrest and apoptosis by positively regulating p53 transcriptional activity
We previously identified JAZ as a novel zinc finger (ZF) protein by screening a murine interleukin-3 (IL-3)–dependent NFS/N1.H7 myeloid cell cDNA library. JAZ is a member of a new class of ZFPs that is evolutionarily conserved and preferentially binds to dsRNA, but its function was unknown. Now, we...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The American Society of Hematology
2006
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895452/ https://ncbi.nlm.nih.gov/pubmed/16931621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-06-029645 |
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