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JAZ mediates G(1) cell-cycle arrest and apoptosis by positively regulating p53 transcriptional activity

We previously identified JAZ as a novel zinc finger (ZF) protein by screening a murine interleukin-3 (IL-3)–dependent NFS/N1.H7 myeloid cell cDNA library. JAZ is a member of a new class of ZFPs that is evolutionarily conserved and preferentially binds to dsRNA, but its function was unknown. Now, we...

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Bibliografiske detaljer
Main Authors: Yang, Mingli, Wu, Song, Su, Xuekun, May, W. Stratford
Format: Artigo
Sprog:Inglês
Udgivet: The American Society of Hematology 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895452/
https://ncbi.nlm.nih.gov/pubmed/16931621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-06-029645
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