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Targeting colorectal cancer stem cells with inducible caspase-9

Colorectal cancer stem cells (CSCs) drive tumor growth and are suggested to initiate distant metastases. Moreover, colon CSCs are reportedly more resistant to conventional chemotherapy, which is in part due to upregulation of anti-apoptotic Bcl-2 family members. To determine whether we could circumv...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Kemper, Kristel, Rodermond, Hans, Colak, Selçuk, Grandela, Catarina, Medema, Jan Paul
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer US 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322325/
https://ncbi.nlm.nih.gov/pubmed/22223359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-011-0692-z
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