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Lack of ATM induces structural and functional changes in the heart: Role in β-adrenergic receptor-stimulated apoptosis
Ataxia telangiectasia mutated kinase (ATM) is involved in cell cycle checkpoints, DNA repair and apoptosis. β-adrenergic receptor (β-AR) stimulation induces cardiac myocyte apoptosis. Here we analyzed basal myocardial structure and function in ATM knockout (KO) mice, and tested the hypothesis that A...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3322313/ https://ncbi.nlm.nih.gov/pubmed/22179422 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/expphysiol.2011.061812 |
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