Lack of ATM induces structural and functional changes in the heart: Role in β-adrenergic receptor-stimulated apoptosis

Ataxia telangiectasia mutated kinase (ATM) is involved in cell cycle checkpoints, DNA repair and apoptosis. β-adrenergic receptor (β-AR) stimulation induces cardiac myocyte apoptosis. Here we analyzed basal myocardial structure and function in ATM knockout (KO) mice, and tested the hypothesis that A...

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Main Authors: Foster, Cerrone R., Zha, QinQin, Daniel, Laura L., Singh, Mahipal, Singh, Krishna
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322313/
https://ncbi.nlm.nih.gov/pubmed/22179422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/expphysiol.2011.061812
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