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β-Adrenergic Receptor Stimulation Induces Endoplasmic Reticulum Stress in Adult Cardiac Myocytes: Role in Apoptosis

Accumulation of misfolded proteins and alterations in calcium homeostasis induces endoplasmic reticulum (ER) stress, leading to apoptosis. Here we tested the hypothesis that β-AR stimulation induces ER stress, and induction of ER stress plays a pro-apoptotic role in cardiac myocytes. Using thapsigar...

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Detalhes bibliográficos
Main Authors: Dalal, Suman, Foster, Cerrone R., Das, Bhudev C., Singh, Mahipal, Singh, Krishna
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320150/
https://ncbi.nlm.nih.gov/pubmed/22270541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-011-1205-7
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