Alzheimer Disease Susceptibility Loci: Evidence for a Protein Network under Natural Selection

Recent genome-wide association studies have identified a number of susceptibility loci for Alzheimer disease (AD). To understand the functional consequences and potential interactions of the associated loci, we explored large-scale data sets interrogating the human genome for evidence of positive na...

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Autores principales: Raj, Towfique, Shulman, Joshua M., Keenan, Brendan T., Chibnik, Lori B., Evans, Denis A., Bennett, David A., Stranger, Barbara E., De Jager, Philip L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322230/
https://ncbi.nlm.nih.gov/pubmed/22482808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2012.02.022
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