Cloned origin of DNA replication in c-myc gene can function and be transmitted in transgenic mice in an episomal state.

The c-myc protein has recently been shown to interact with a region possessing putative origin of DNA replication and enhancer activities located 2 kb upstream of the c-myc gene itself. Transgenic mice were obtained by injecting constructs containing this region, termed pmyc(H-P), into fertilized mo...

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Publié dans:	Nucleic Acids Res
Auteurs principaux:	Sudo, K, Ogata, M, Sato, Y, Iguchi-Ariga, S M, Ariga, H
Format:	Artigo
Langue:	Inglês
Publié:	Oxford University Press 1990
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC332220/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2216716/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.18.5425
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