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c-myc protein can be substituted for SV40 T antigen in SV40 DNA replication.
Replicating activity of SV40 origin-containing plasmid was tested in human cells as well as in monkey CosI cells. All the plasmids possessing SV40 ori sequences could replicate, even in the absence of SV40 T antigen, in human HL-60 and Raji cells which are expressing c-myc gene at high level. The co...
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| Главные авторы: | , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
1987
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| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC305925/ https://ncbi.nlm.nih.gov/pubmed/3037484 |
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