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c-myc protein can be substituted for SV40 T antigen in SV40 DNA replication.

Replicating activity of SV40 origin-containing plasmid was tested in human cells as well as in monkey CosI cells. All the plasmids possessing SV40 ori sequences could replicate, even in the absence of SV40 T antigen, in human HL-60 and Raji cells which are expressing c-myc gene at high level. The co...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Iguchi-Ariga, S M, Itani, T, Yamaguchi, M, Ariga, H
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 1987
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305925/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3037484/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/15.12.4889
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