Cloned origin of DNA replication in c-myc gene can function and be transmitted in transgenic mice in an episomal state.
The c-myc protein has recently been shown to interact with a region possessing putative origin of DNA replication and enhancer activities located 2 kb upstream of the c-myc gene itself. Transgenic mice were obtained by injecting constructs containing this region, termed pmyc(H-P), into fertilized mo...
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| Publicado en: | Nucleic Acids Res |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
1990
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| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC332220/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2216716/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.18.5425 |
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