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Site specific functionalization of oligonucleotides for attaching two different reporter groups.

The synthesis of an oligonucleotide functionalized to attach two different reporter groups at specific internucleotide linkages is described. To incorporate the amine specific reporter group the internucleotide linkage is modified to phosphoramidate (N-1-aminoalkyl) and for a thiol specific reporter...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Agrawal, S, Zamecnik, P C
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1990
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC332219/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2216715/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.18.5419
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