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Site specific functionalization of oligonucleotides for attaching two different reporter groups.

The synthesis of an oligonucleotide functionalized to attach two different reporter groups at specific internucleotide linkages is described. To incorporate the amine specific reporter group the internucleotide linkage is modified to phosphoramidate (N-1-aminoalkyl) and for a thiol specific reporter...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Agrawal, S, Zamecnik, P C
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 1990
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC332219/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2216715/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.18.5419
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