Site specific functionalization of oligonucleotides for attaching two different reporter groups.

The synthesis of an oligonucleotide functionalized to attach two different reporter groups at specific internucleotide linkages is described. To incorporate the amine specific reporter group the internucleotide linkage is modified to phosphoramidate (N-1-aminoalkyl) and for a thiol specific reporter...

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Publicado en:	Nucleic Acids Res
Autores principales:	Agrawal, S, Zamecnik, P C
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Oxford University Press 1990
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC332219/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2216715/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.18.5419
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