Methylation of AR locus does not always reflect X chromosome inactivation state

Clonality can be established by a lack of mosaicism in a female because of random inactivation of either the maternal or paternal X chromosome early in embryogenesis. The methylation status of CpG sites close to the trinucleotide repeats in exon 1 of the human androgen receptor (AR) X chromosome gen...

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Dades bibliogràfiques
Autors principals: Swierczek, Sabina I., Piterkova, Lucie, Jelinek, Jaroslav, Agarwal, Neeraj, Hammoud, Sue, Wilson, Andrew, Hickman, Kimberly, Parker, Charles J., Cairns, Bradley, Prchal, Josef T.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2012
Matèries:
Hematopoiesis and Stem Cells
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321879/
https://ncbi.nlm.nih.gov/pubmed/22286197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-11-390351
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