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Convergent Mechanisms of Somatic Mutations in Polycythemia Vera

Polycythemia vera (PV) is an acquired blood disorder, with variable increase of clonal myeloid cells (erythrocytes, granulocytes and platelets) and mostly normal polyclonal T lymphocytes. Most patients have a somatic V617F gain-of-function mutation in JAK2 associated with acquired uniparental disomy...

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Bibliografiske detaljer
Udgivet i:Discov Med
Main Authors: Wang, Kai, Swierczek, Sabina, Hickman, Kimberly, Prchal, Josef T., Hakonarson, Hakon
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347892/
https://ncbi.nlm.nih.gov/pubmed/21794206
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