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Convergent Mechanisms of Somatic Mutations in Polycythemia Vera

Polycythemia vera (PV) is an acquired blood disorder, with variable increase of clonal myeloid cells (erythrocytes, granulocytes and platelets) and mostly normal polyclonal T lymphocytes. Most patients have a somatic V617F gain-of-function mutation in JAK2 associated with acquired uniparental disomy...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Discov Med
Prif Awduron: Wang, Kai, Swierczek, Sabina, Hickman, Kimberly, Prchal, Josef T., Hakonarson, Hakon
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347892/
https://ncbi.nlm.nih.gov/pubmed/21794206
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