Whole-exome sequencing of polycythemia vera revealed novel driver genes and somatic mutation shared by T-cells and granulocytes

To better understand the underlying molecular basis of polycythemia vera (PV), we performed whole-exome sequencing and DNA copy-number analysis of 31 JAK2(V617F)-positive patients and further investigated the evolution of somatic mutations using longitudinal samples. In addition to JAK2(V617F) and 9...

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Vydáno v:Leukemia
Hlavní autoři: Wang, Linghua, Swierczek, Sabina I., Drummond, Jennifer, Hickman, Kimberly, Walker, Kimberly, Doddapaneni, Harshavardhan, Muzny, Donna M., Gibbs, Richard A., Wheeler, David A., Prchal, Josef T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4532385/
https://ncbi.nlm.nih.gov/pubmed/24413320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2014.7
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