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PKD is a kinase of Vps34 that mediates ROS-induced autophagy downstream of DAPk
Autophagy, a process in which cellular components are engulfed and degraded within double-membrane vesicles termed autophagosomes, has an important role in the response to oxidative damage. Here we identify a novel cascade of phosphorylation events, involving a network of protein and lipid kinases,...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3321617/ https://ncbi.nlm.nih.gov/pubmed/22095288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.149 |
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