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PKD is a kinase of Vps34 that mediates ROS-induced autophagy downstream of DAPk

Autophagy, a process in which cellular components are engulfed and degraded within double-membrane vesicles termed autophagosomes, has an important role in the response to oxidative damage. Here we identify a novel cascade of phosphorylation events, involving a network of protein and lipid kinases,...

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Detalhes bibliográficos
Main Authors: Eisenberg-Lerner, A, Kimchi, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321617/
https://ncbi.nlm.nih.gov/pubmed/22095288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.149
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