Enhancing Muscle Membrane Repair by Gene Delivery of MG53 Ameliorates Muscular Dystrophy and Heart Failure in δ-Sarcoglycan-deficient Hamsters

Muscular dystrophies (MDs) are caused by genetic mutations in over 30 different genes, many of which encode for proteins essential for the integrity of muscle cell structure and membrane. Their deficiencies cause the muscle vulnerable to mechanical and biochemical damages, leading to membrane leakag...

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Detalhes bibliográficos
Main Authors: He, Bo, Tang, Ru-hang, Weisleder, Noah, Xiao, Bin, Yuan, Zhenhua, Cai, Chuanxi, Zhu, Hua, Lin, Peihui, Qiao, Chunping, Li, Jianbin, Mayer, Christina, Li, Juan, Ma, Jianjie, Xiao, Xiao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321592/
https://ncbi.nlm.nih.gov/pubmed/22314291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.5
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