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Progressive Muscular Dystrophy in α-Sarcoglycan–deficient Mice

Limb-girdle muscular dystrophy type 2D (LGMD 2D) is an autosomal recessive disorder caused by mutations in the α-sarcoglycan gene. To determine how α-sarcoglycan deficiency leads to muscle fiber degeneration, we generated and analyzed α-sarcoglycan– deficient mice. Sgca-null mice developed progressi...

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Detalhes bibliográficos
Main Authors: Duclos, Franck, Straub, Volker, Moore, Steven A., Venzke, David P., Hrstka, Ron F., Crosbie, Rachelle H., Durbeej, Madeleine, Lebakken, Connie S., Ettinger, Audrey J., van der Meulen, Jack, Holt, Kathleen H., Lim, Leland E., Sanes, Joshua R., Davidson, Beverly L., Faulkner, John A., Williamson, Roger, Campbell, Kevin P.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2141773/
https://ncbi.nlm.nih.gov/pubmed/9744877
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